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Ilya Bezprozvanny Selected Research

latrepirdine (dimebon)

10/2010The rise and fall of Dimebon.
12/2009Acute dosing of latrepirdine (Dimebon), a possible Alzheimer therapeutic, elevates extracellular amyloid-beta levels in vitro and in vivo.
10/2008Evaluation of Dimebon in cellular model of Huntington's disease.

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Ilya Bezprozvanny Research Topics

Disease

32Alzheimer Disease (Alzheimer's Disease)
06/2022 - 09/2006
24Huntington Disease (Huntington's Disease)
01/2019 - 07/2003
16Neurodegenerative Diseases (Neurodegenerative Disease)
04/2021 - 07/2007
6Spinocerebellar Ataxias (Spinocerebellar Ataxia)
10/2012 - 07/2009
4Machado-Joseph Disease (Spinocerebellar Ataxia Type 3)
11/2011 - 11/2008
3Cognitive Dysfunction
09/2011 - 02/2010
2Amyloid Plaque
08/2015 - 03/2009
2Atrophy
09/2012 - 06/2010
1Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)
01/2019
1Nervous System Diseases (Neurological Disorders)
01/2019
1Frontotemporal Dementia (Semantic Dementia)
01/2019
1Neoplasms (Cancer)
10/2017
1Memory Disorders (Memory Loss)
11/2016
1Autistic Disorder (Autism)
01/2016
1Neuroinflammatory Diseases
01/2016
1Cerebellar Ataxia (Dysmetria)
10/2012
1Ataxia (Dyssynergia)
09/2012
1Hypersensitivity (Allergy)
10/2010
1Spastic Paraparesis
01/2010
1Neuroblastoma
12/2009
1Infections
02/2009
1Dementia (Dementias)
05/2007
1Herpes Zoster
02/2005
1Carcinoma (Carcinomatosis)
07/2003

Drug/Important Bio-Agent (IBA)

21CalciumIBA
06/2022 - 07/2003
17polyglutamineIBA
01/2021 - 07/2003
15Proteins (Proteins, Gene)FDA Link
12/2021 - 02/2005
9Amyloid (Amyloid Fibrils)IBA
12/2021 - 03/2009
9PresenilinsIBA
10/2017 - 09/2006
6Huntingtin ProteinIBA
01/2014 - 07/2007
6Flavin-Adenine Dinucleotide (FAD)IBA
07/2013 - 01/2010
5Amyloid beta-PeptidesIBA
02/2022 - 03/2009
5Peptides (Polypeptides)IBA
08/2015 - 03/2009
4Sigma-1 ReceptorIBA
04/2021 - 01/2017
3pridopidineIBA
01/2019 - 01/2017
3Inositol 1,4,5-Trisphosphate Receptors (Inositol Triphosphate Receptor)IBA
09/2012 - 02/2009
3latrepirdine (dimebon)IBA
10/2010 - 10/2008
3Glutamic Acid (Glutamate)FDA Link
09/2010 - 10/2006
2Neuroprotective AgentsIBA
01/2019 - 02/2009
2Ryanodine Receptor Calcium Release Channel (Ryanodine Receptor)IBA
01/2014 - 11/2011
2Ataxin-2IBA
10/2012 - 07/2009
2Amyloid Precursor Protein Secretases (beta-Secretase)IBA
07/2012 - 06/2011
2Dantrolene (Dantrium)FDA LinkGeneric
11/2011 - 06/2010
2Presenilin-1IBA
06/2011 - 05/2007
2Histamine Antagonists (Antihistamines)IBA
10/2010 - 12/2009
2Ataxin-3IBA
05/2009 - 11/2008
1Calcium-Calmodulin-Dependent Protein Kinase Type 2IBA
06/2022
1Calcium-Calmodulin-Dependent Protein KinasesIBA
06/2022
1Apolipoprotein E4IBA
05/2021
1Biological ProductsIBA
05/2021
1Protein Isoforms (Isoforms)IBA
05/2021
1Apolipoproteins E (ApoE)IBA
05/2021
1CholesterolIBA
04/2021
1Glutamine (L-Glutamine)FDA Link
01/2021
1PiperazinesIBA
01/2019
1Heme (Haem)IBA
01/2019
1LigandsIBA
01/2019
1Peptide Hydrolases (Proteases)FDA Link
10/2017
1NucleotidesIBA
01/2017
1TRPC6 Cation ChannelIBA
11/2016
1Calcium Channels (Calcium Channel)IBA
11/2016
1ChromatinIBA
01/2016
1Calcium-Activated Potassium Channels (Calcium-Activated Potassium Channel)IBA
10/2012
14- (chlorophenyl)- (2- (3,5- dimethylpyrazol- 1- yl)- 9- methyl- 9H- purin- 6- yl)amineIBA
10/2012
1PeptoidsIBA
09/2011
1Presenilin-2IBA
06/2011
1Dopamine (Intropin)FDA LinkGeneric
09/2010
1Tetrabenazine (Nitoman)FDA Link
04/2010
1GinsenosidesIBA
06/2009